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Jacob Madsen Selected Research

1- (1,3- carboxypropyl)- 4,7- carboxymethyl- 1,4,7- triazacyclononane

3/2022First-in-Human Study of [68Ga]Ga-NODAGA-E[c(RGDyK)]2 PET for Integrin αvβ3 Imaging in Patients with Breast Cancer and Neuroendocrine Neoplasms: Safety, Dosimetry and Tumor Imaging Ability.
5/2018Angiogenesis PET Tracer Uptake (68Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction and Stromal Cell Treatment in Minipigs.
6/2016Angiogenesis PET Tracer Uptake ((68)Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction in Minipigs.
3/2014Comparison of two new angiogenesis PET tracers 68Ga-NODAGA-E[c(RGDyK)]2 and (64)Cu-NODAGA-E[c(RGDyK)]2; in vivo imaging studies in human xenograft tumors.
5/201268Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers.

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Jacob Madsen Research Topics

Disease

22Neoplasms (Cancer)
12/2022 - 01/2012
5Prostatic Neoplasms (Prostate Cancer)
06/2021 - 07/2013
5Mood Disorders (Mood Disorder)
01/2016 - 02/2008
5Ovarian Neoplasms (Ovarian Cancer)
04/2013 - 09/2010
4Neoplasm Metastasis (Metastasis)
03/2022 - 05/2015
4Schizophrenia (Dementia Praecox)
01/2016 - 09/2008
3Glioblastoma (Glioblastoma Multiforme)
02/2016 - 01/2014
2Breast Neoplasms (Breast Cancer)
03/2022 - 01/2017
2Seasonal Affective Disorder
10/2018 - 01/2016
2Myocardial Infarction
05/2018 - 06/2016
2Urinary Bladder Neoplasms (Bladder Cancer)
01/2017 - 01/2015
1COVID-19
01/2022
1Parkinson Disease (Parkinson's Disease)
06/2021
1Respiratory Insufficiency (Respiratory Failure)
10/2016
1Glioma (Gliomas)
02/2016
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2016
1Thrombosis (Thrombus)
05/2015
1Psychotic Disorders (Schizoaffective Disorder)
01/2013
1Colorectal Neoplasms (Colorectal Cancer)
10/2012
1Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2012
1Colonic Neoplasms (Colon Cancer)
01/2012
1Alzheimer Disease (Alzheimer's Disease)
09/2011
1Anxiety Disorders (Anxiety Disorder)
10/2010
1Hypoxia (Hypoxemia)
06/2009
1Mental Disorders (Mental Disorder)
09/2008
1Neurodegenerative Diseases (Neurodegenerative Disease)
02/2008
1Feeding and Eating Disorders (Eating Disorder)
02/2008

Drug/Important Bio-Agent (IBA)

8Urokinase Plasminogen Activator ReceptorsIBA
01/2021 - 01/2012
6Biomarkers (Surrogate Marker)IBA
01/2017 - 01/2012
5Thromboplastin (Tissue Factor)IBA
12/2022 - 01/2016
51- (1,3- carboxypropyl)- 4,7- carboxymethyl- 1,4,7- triazacyclononaneIBA
03/2022 - 05/2012
4LigandsIBA
12/2022 - 01/2013
4Serotonin (5 Hydroxytryptamine)IBA
10/2018 - 02/2008
45-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
01/2016 - 09/2008
4alovudineIBA
04/2013 - 09/2010
3IntegrinsIBA
03/2022 - 01/2012
3Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
01/2016 - 06/2009
2Factor VII (Proconvertin)IBA
12/2022 - 01/2016
2EnzymesIBA
01/2016 - 01/2012
2ImmunosorbentsIBA
01/2016 - 01/2012
2Radioisotopes (Radionuclides)IBA
08/2014 - 10/2012
2Glucose (Dextrose)FDA LinkGeneric
04/2013 - 01/2013
21,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA
05/2012 - 01/2012
2Peptides (Polypeptides)IBA
05/2012 - 01/2012
2Antipsychotic Agents (Antipsychotics)IBA
01/2010 - 09/2008
1Glycine (Aminoacetic Acid)FDA LinkGeneric
03/2022
1Aspartic Acid (Aspartate)FDA Link
03/2022
1Dihydrotachysterol (AT 10)IBA
03/2022
1Arginine (L-Arginine)FDA Link
03/2022
1RadiopharmaceuticalsIBA
06/2021
1Radium-223IBA
06/2021
1Proteins (Proteins, Gene)FDA Link
01/2019
1Trastuzumab (Herceptin)FDA Link
01/2019
1BuffersIBA
01/2019
1Copper-64IBA
01/2019
1Membrane Proteins (Integral Membrane Proteins)IBA
01/2018
11,4,7- triazacyclononane- N,N',N''- triacetic acid (NOTA)IBA
01/2017
1Messenger RNA (mRNA)IBA
02/2016
1Pharmaceutical PreparationsIBA
01/2016
1Glycoproteins (Glycoprotein)IBA
05/2015
1Irinotecan (Camptosar)FDA LinkGeneric
01/2014
1Amino Acid Transport Systems (Amino Acid Transporter)IBA
01/2014
1cupric chloride (copper(II) chloride)FDA Link
04/2013
1Hydrocortisone (Cortisol)FDA LinkGeneric
04/2013
1Histone Deacetylase InhibitorsIBA
04/2013
1Copper Transporter 1IBA
04/2013
1belinostatIBA
04/2013
1CopperIBA
04/2013
1Adrenergic Receptors (Adrenergic Receptor)IBA
01/2013
1Carboplatin (JM8)FDA LinkGeneric
01/2013
1N- (4- (1- benzoylpiperidin- 4- yl)butyl)- 3- (pyridin- 3- yl)acrylamideIBA
01/2013
1Paclitaxel (Taxol)FDA LinkGeneric
01/2013
1Nicotinamide PhosphoribosyltransferaseIBA
01/2013
1Peptide Receptors (Peptide Receptor)IBA
10/2012
1177Lu-DOTA-AE105IBA
10/2012
1TP202377IBA
01/2012
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2012
1Fluorouracil (Carac)FDA LinkGeneric
01/2012
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
09/2011
1Gonadal Steroid Hormones (Sex Hormones)IBA
10/2010
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
06/2009
1Carbonic Anhydrase IIIIBA
06/2009
1altanserinIBA
09/2008

Therapy/Procedure

5Therapeutics
06/2021 - 01/2012
3Aftercare (After-Treatment)
04/2013 - 01/2012
2Precision Medicine
08/2014 - 10/2012
2Drug Therapy (Chemotherapy)
01/2013 - 01/2012
1Length of Stay
01/2022
1Castration
06/2021
1Continuous Positive Airway Pressure
10/2016
1Radiotherapy
08/2014